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Wednesday, July 22, 2020 | History

5 edition of Biology of the sialic acids found in the catalog.

Biology of the sialic acids

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Published by Plenum Press in New York .
Written in English

    Subjects:
  • Sialic acids -- Physiological effect

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Abraham Rosenberg.
    ContributionsRosenberg, Abraham, 1924-
    Classifications
    LC ClassificationsQP801.S47 B566 1995
    The Physical Object
    Paginationxv, 378 p. :
    Number of Pages378
    ID Numbers
    Open LibraryOL786945M
    ISBN 100306449749
    LC Control Number95019224

    Unlike monosaccharides, nucleotides, and amino acids, fatty acids are not monomers that are linked together to form much larger molecules. Although fatty acids can be linked together, for example, into triacylglycerols or phospholipids, they are not linked directly to one another, and generally no more than three in a given molecule. CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.. It binds sialic acids, therefore is a member of the SIGLEC family of lectinsAliases: CD33, CD33 molecule, SIGLEC-3, SIGLEC3, p

    G. Reuter, S. Stoll, J.P. Kamerling, J.F. Vliegenthart and R. Schauer () Sialic acids on erythrocytes and in blood plasma of mammals, in: Sialic Acids - Proceedings of the Japanese-German Symposium on Sialic Acids (R. Schauer and T. Yamakawa, Cited by:   While many chemicals are important in this milieu, here we focus on sialic acids as a critical set of molecules that underpin many of these interactions and impact on metabolism, health and disease. The most common sialic acid, N -acetyl-neuraminic acid (Neu5Ac) (Fig. 1) is a relatively simple sugar acid that, apart from its charge, has nothing.

    Sialic acids (neuraminic acids) are a diverse family of nine carbon (nonulosonic) α-keto acidic carbohydrates. The canonical sialic acid, 2-ketodeoxyacetamido-D-glycero-D-galacto-nonulosonic acid, also known as N-acetylneuraminic acid (Neu5Ac) is the backbone on which a large number of known modifications are made (1). The Neu5Ac structure is typified by a 6-carbon carboxylic acid Cited by: Sialic acids: Chemistry, metabolism and function (Cell biology monographs, vol. 10) edited by R. Schauer, Springer-Verlag, DM /US $ (xvii + ) ISBN 3 7 (German edition) ISBN 0 7 (English edition)Cited by:


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Biology of the sialic acids Download PDF EPUB FB2

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. InA. GOTTSCHALK wrote "The Chemistry and Biology of Sialic Acids and Related Substances" (Cambridge University Press) and inA.

ROSENBERG and C. SCHENGRUND published "Biological Roles of Sialic Acids" (Plenum Press). In this book emphasis is given to various modern methods used in the isolation and analysis of sialic acids. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid.

Outstanding features of this work include exhaustive reference material and detailed information tables. Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology.

This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid.

Get this from a library. Biology of the sialic acids. [Abraham Rosenberg;] -- Abraham Rosenberg assembles the groundbreaking work of Biology of the sialic acids book international scientists to provide the most current, state-of-the-art presentation of research in siabiology.

This concise volume. Sialic acids comprise a family of more than 50 naturally occurring carbohydrates that are derivatives of the nine-carbon sugar neuraminic acid (5-amino-3,5-dideoxy-d-glycero-d-galactononulsonic acid).One branch of the sialic acid family is N-acetylated to form N-acetylneuraminic acids, which are the most common form of sialic acid in humans [50].In human serum, the majority of sialic acid is N.

About this book This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid.

Biology of the Sialic Acids: Medicine & Health Science Books @ Skip to main content. Try Prime Hello, Sign in Account & Lists Sign in Account & Lists Orders Try Prime Cart.

Books. Go Search Today's Deals Best Sellers Find a Gift Customer Service New. : Sialic Acids: "Chemistry, Metabolism, and Function" (Cell Biology Monographs) (): Roland Schauer: Books. ISBN: OCLC Number: Description: xv, pages: illustrations ; 24 cm: Contents: Beginnings of sialic acid / Abraham Rosenberg --Biochemistry and role of sialic acids / Roland Schauer [et al.] --Biological specificity of sialytransferases / Subhash Basu, Manju Basu, and Shib Sankar Basar --Sialobiology and the polysialic acid glycotope: occurrence.

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational book provides insights on the latest knowledge in the field of sialoglycobiology.

This chapter describes the sialic acid family of monosaccharides, with respect to their biosynthesis, structural diversity, and linkage to the underlying glycan chain. Also mentioned are the general principles behind different methods for their study.

The biological and pathophysiological roles of sialic acids are briefly considered, particularly the functional significance of lectins that. Higa, H.

H., Butor, C., Diaz, S., and Varki, A., a, 0-Acetylation and de-O-acetylation of sialic acids. 0-Acetylation of sialic acids in rat liver Golgi apparatus involves an acetyl intermediate and essential histidine and lysine residues—A transmembrane reaction.

Cited by: Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis, biology, and evolution of saccharides (sugar chains or glycans) that are widely distributed in nature in all living life forms.

Glycobiology is now one of the more rapidly growing fields in the natural sciences, with broad relevance to many areas of basic research, biomedicine, and by: Sialic acids exert their function in biology through multiple mechanisms as they are directly and indirectly involved in numerous events at both the molecular and cellular level [2, 3].

Several of. Sialic Acids, Vol the most recent release in the Advances in Carbohydrate Chemistry and Biochemistry series, is the second volume of a two-volume set devoted to the sialic 76, devoted to the biological and biomedical aspects of sialic acids, includes chapters on "Sialic Acids in Neurology," "Sialic Acids in Nonenveloped Virus Infections," and "The Biology of Gangliosides.

sialic acids decorate the canopy of the cell-surface glycan forest and have multiple biological roles In the Deuterostome lineage (vertebrates and so-called “higher” invertebrates) the outer ends of glycan chains are often capped by sialic acids (Sias) (Varki, ; Schauer, ).

Sialic acid is a generic term for a family of derivatives of neuraminic acid, an acidic sugar with a nine-carbon backbone. It is also the name for the most common member of this group, N-acetylneuraminic acid (Neu5Ac or NANA).

Sialic acids are found widely distributed in animal tissues and to a lesser extent in other organisms, ranging from fungi to yeasts and bacteria, mostly in glycoproteins.

InA. GOTTSCHALK wrote "The Chemistry and Biology of Sialic Acids and Related Substances" (Cambridge University Press) and inA. ROSENBERG and C. Sialic acids are a family of nine-carbon sugars that are typically found at the terminal end of glycan chains on the cell surface and secreted molecules in the deuterostome lineage of animals (Angata and Varki ; Schauer ; Varki ) (Fig.

a).The two most common forms of sialic acid are N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), and Neu5Gc is Cited by: 2. Sialic acids (SAs) are typically found as terminal monosaccharides attached to cell surface glycoconjugates, which play crucial roles in various biological processes, and aberrant sialylation is closely associated with many diseases, particularly cancers.

As SAs are overexpressed in tumor-associated glycoproteins, the recognition and specific binding of SA are crucial for monitoring, Cited by: 6.Sialic acids are a subset of nonulosonic acids, which are nine-carbon α-keto aldonic acids.

Natural existing sialic acid-containing structures are presented in different sialic acid forms, various sialyl linkages, and on diverse underlying glycans. They play important roles in biological, pathological, and immunological processes.Sialic acids, a subset of nine carbon acidic sugars, often exist as the terminal sugars of glycans on either glycoproteins or glycolipids on the cell surface.

Sialic acids play important roles in many physiological and pathological processes via carbohydrate-protein interactions, including cell–cell communication, bacterial and viral infections. In particular, hypersialylation in tumors Author: Xiaoman Zhou, Ganglong Yang, Feng Guan.